PubMed Link to all articles published by the members of this lab.
Publications
1: The genome of Brugia malayi - All worms are not created equal.
Scott AL, Ghedin E.
Parasitol Int. 2009 Mar;58(1):6-11. Epub 2008 Sep 24.
PMID: 18952001
Alekseev KP, Vlasova AN, Jung K, Hasoksuz M, Zhang X, Halpin R, Wang S, Ghedin E, Spiro D, Saif LJ.
J Virol. 2008 Dec;82(24):12422-31. Epub 2008 Oct 8.
PMID: 18842722
Nelson MI, Edelman L, Spiro DJ, Boyne AR, Bera J, Halpin R, Sengamalay N, Ghedin E, Miller MA, Simonsen L, Viboud C, Holmes EC.
PLoS Pathog. 2008 Aug 22;4(8):e1000133. Erratum in: PLoS Pathog. 2008 Dec;4(12). doi.org//10.1371/annotation/1391941e-93d3-48d3-8c9a-b7c6d98f9527.. Sengamalay, Naomi [added].
PMID: 18725925
4: The evolutionary genetics and emergence of avian influenza viruses in wild birds.
Dugan VG, Chen R, Spiro DJ, Sengamalay N, Zaborsky J, Ghedin E, Nolting J, Swayne DE, Runstadler JA, Happ GM, Senne DA, Wang R, Slemons RD, Holmes EC, Taubenberger JK.
PLoS Pathog. 2008 May 30;4(5):e1000076.
PMID: 18516303
5: Role of transposable elements in trypanosomatids.
Bringaud F, Ghedin E, El-Sayed NM, Papadopoulou B.
Microbes Infect. 2008 May;10(6):575-81. Epub 2008 Feb 21. Review.
PMID: 18467144
6: Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918.
Nelson MI, Viboud C, Simonsen L, Bennett RT, Griesemer SB, St George K, Taylor J, Spiro DJ, Sengamalay NA, Ghedin E, Taubenberger JK, Holmes EC.
PLoS Pathog. 2008 Feb 29;4(2):e1000012.
PMID: 18463694
7: Viral genome sequencing by random priming methods.
Djikeng A, Halpin R, Kuzmickas R, Depasse J, Feldblyum J, Sengamalay N, Afonso C, Zhang X, Anderson NG, Ghedin E, Spiro DJ.
BMC Genomics. 2008 Jan 7;9:5.
PMID: 18179705
8: Genes encoding putative biogenic amine receptors in the parasitic nematode Brugia malayi.
Smith KA, Komuniecki RW, Ghedin E, Spiro D, Gray J.
Invert Neurosci. 2007 Dec;7(4):227-44. Epub 2007 Nov 20.
PMID: 18027007
9: Mining predicted essential genes of Brugia malayi for nematode drug targets.
Kumar S, Chaudhary K, Foster JM, Novelli JF, Zhang Y, Wang S, Spiro D, Ghedin E, Carlow CK.
PLoS ONE. 2007 Nov 14;2(11):e1189.
PMID: 18000556
10: Sequences necessary for trans-splicing in transiently transfected Brugia malayi.
Liu C, de Oliveira A, Higazi TB, Ghedin E, DePasse J, Unnasch TR.
Mol Biochem Parasitol. 2007 Nov;156(1):62-73. Epub 2007 Jul 22.
PMID: 17727976
11: Draft genome of the filarial nematode parasite Brugia malayi.
Ghedin E, Wang S, Spiro D, Caler E, Zhao Q, Crabtree J, Allen JE, Delcher AL, Guiliano DB, Miranda-Saavedra D, Angiuoli SV, Creasy T, Amedeo P, Haas B, El-Sayed NM, Wortman JR, Feldblyum T, Tallon L, Schatz M, Shumway M, Koo H, Salzberg SL, Schobel S, Pertea M, Pop M, White O, Barton GJ, Carlow CK, Crawford MJ, Daub J, Dimmic MW, Estes CF, Foster JM, Ganatra M, Gregory WF, Johnson NM, Jin J, Komuniecki R, Korf I, Kumar S, Laney S, Li BW, Li W, Lindblom TH, Lustigman S, Ma D, Maina CV, Martin DM, McCarter JP, McReynolds L, Mitreva M, Nutman TB, Parkinson J, Peregrín-Alvarez JM, Poole C, Ren Q, Saunders L, Sluder AE, Smith K, Stanke M, Unnasch TR, Ware J, Wei AD, Weil G, Williams DJ, Zhang Y, Williams SA, Fraser-Liggett C, Slatko B, Blaxter ML, Scott AL.
Science. 2007 Sep 21;317(5845):1756-60.
PMID: 17885136
12: Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes.
Hotopp JC, Clark ME, Oliveira DC, Foster JM, Fischer P, Torres MC, Giebel JD, Kumar N, Ishmael N, Wang S, Ingram J, Nene RV, Shepard J, Tomkins J, Richards S, Spiro DJ, Ghedin E, Slatko BE, Tettelin H, Werren JH.
Science. 2007 Sep 21;317(5845):1753-6. Epub 2007 Aug 30.
PMID: 17761848
Bringaud F, Müller M, Cerqueira GC, Smith M, Rochette A, El-Sayed NM, Papadopoulou B, Ghedin E.
PLoS Pathog. 2007 Sep 7;3(9):1291-307.
PMID: 17907803
Zhang X, Hasoksuz M, Spiro D, Halpin R, Wang S, Vlasova A, Janies D, Jones LR, Ghedin E, Saif LJ.
Virology. 2007 Jun 20;363(1):1-10. Epub 2007 Apr 16.
PMID: 17434558
15: Genome analysis linking recent European and African influenza (H5N1) viruses.
Salzberg SL, Kingsford C, Cattoli G, Spiro DJ, Janies DA, Aly MM, Brown IH, Couacy-Hymann E, De Mia GM, Dung do H, Guercio A, Joannis T, Maken Ali AS, Osmani A, Padalino I, Saad MD, Savić V, Sengamalay NA, Yingst S, Zaborsky J, Zorman-Rojs O, Ghedin E, Capua I.
Emerg Infect Dis. 2007 May;13(5):713-8.
PMID: 17553249
Hasoksuz M, Alekseev K, Vlasova A, Zhang X, Spiro D, Halpin R, Wang S, Ghedin E, Saif LJ.
J Virol. 2007 May;81(10):4981-90. Epub 2007 Mar 7.
PMID: 17344285
Zhang X, Hasoksuz M, Spiro D, Halpin R, Wang S, Stollar S, Janies D, Hadya N, Tang Y, Ghedin E, Saif L.
Virology. 2007 Feb 20;358(2):424-35. Epub 2006 Oct 4.
PMID: 17023013
Yao K, Akyani N, Donati D, Sengamalay N, Fotheringham J, Ghedin E, Bishop M, Barrett J, Kashanchi F, Jacobson S.
J Clin Virol. 2006 Dec;37 Suppl 1:S57-62.
PMID: 17276371
19: Stochastic processes are key determinants of short-term evolution in influenza a virus.
Nelson MI, Simonsen L, Viboud C, Miller MA, Taylor J, George KS, Griesemer SB, Ghedin E, Sengamalay NA, Spiro DJ, Volkov I, Grenfell BT, Lipman DJ, Taubenberger JK, Holmes EC.
PLoS Pathog. 2006 Dec;2(12):e125. Erratum in: PLoS Pathog. 2006 Dec;2(12):e138. Ghedi, Elodie [corrected to Ghedin, Elodie].
PMID: 17140286
Yao K, Mandel M, Akyani N, Maynard K, Sengamalay N, Fotheringham J, Ghedin E, Kashanchi F, Jacobson S.
Glia. 2006 Jun;53(8):789-98.
PMID: 16541415
21: Shared data are key to beating threat from flu.
Salzberg S, Ghedin E, Spiro D.
Nature. 2006 Mar 30;440(7084):605. No abstract available.
PMID: 16572147
Bringaud F, Ghedin E, Blandin G, Bartholomeu DC, Caler E, Levin MJ, Baltz T, El-Sayed NM.
Mol Biochem Parasitol. 2006 Feb;145(2):158-70. Epub 2005 Oct 10.
PMID: 16257065
Bringaud F, Bartholomeu DC, Blandin G, Delcher A, Baltz T, El-Sayed NM, Ghedin E.
Mol Biol Evol. 2006 Feb;23(2):411-20. Epub 2005 Nov 2.
PMID: 16267142
24: Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution.
Ghedin E, Sengamalay NA, Shumway M, Zaborsky J, Feldblyum T, Subbu V, Spiro DJ, Sitz J, Koo H, Bolotov P, Dernovoy D, Tatusova T, Bao Y, St George K, Taylor J, Lipman DJ, Fraser CM, Taubenberger JK, Salzberg SL.
Nature. 2005 Oct 20;437(7062):1162-6. Epub 2005 Oct 5.
PMID: 16208317
Holmes EC, Ghedin E, Miller N, Taylor J, Bao Y, St George K, Grenfell BT, Salzberg SL, Fraser CM, Lipman DJ, Taubenberger JK.
PLoS Biol. 2005 Sep;3(9):e300. Epub 2005 Jul 26.
PMID: 16026181
26: Mimivirus relatives in the Sargasso sea.
Ghedin E, Claverie JM.
Virol J. 2005 Aug 16;2:62.
PMID: 16105173 [PubMed]
27: The genome of the African trypanosome Trypanosoma brucei.
Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Böhme U, Hannick L, Aslett MA, Shallom J, Marcello L, Hou L, Wickstead B, Alsmark UC, Arrowsmith C, Atkin RJ, Barron AJ, Bringaud F, Brooks K, Carrington M, Cherevach I, Chillingworth TJ, Churcher C, Clark LN, Corton CH, Cronin A, Davies RM, Doggett J, Djikeng A, Feldblyum T, Field MC, Fraser A, Goodhead I, Hance Z, Harper D, Harris BR, Hauser H, Hostetler J, Ivens A, Jagels K, Johnson D, Johnson J, Jones K, Kerhornou AX, Koo H, Larke N, Landfear S, Larkin C, Leech V, Line A, Lord A, Macleod A, Mooney PJ, Moule S, Martin DM, Morgan GW, Mungall K, Norbertczak H, Ormond D, Pai G, Peacock CS, Peterson J, Quail MA, Rabbinowitsch E, Rajandream MA, Reitter C, Salzberg SL, Sanders M, Schobel S, Sharp S, Simmonds M, Simpson AJ, Tallon L, Turner CM, Tait A, Tivey AR, Van Aken S, Walker D, Wanless D, Wang S, White B, White O, Whitehead S, Woodward J, Wortman J, Adams MD, Embley TM, Gull K, Ullu E, Barry JD, Fairlamb AH, Opperdoes F, Barrell BG, Donelson JE, Hall N, Fraser CM, Melville SE, El-Sayed NM.
Science. 2005 Jul 15;309(5733):416-22.
PMID: 16020726
28: The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease.
El-Sayed NM, Myler PJ, Bartholomeu DC, Nilsson D, Aggarwal G, Tran AN, Ghedin E, Worthey EA, Delcher AL, Blandin G, Westenberger SJ, Caler E, Cerqueira GC, Branche C, Haas B, Anupama A, Arner E, Aslund L, Attipoe P, Bontempi E, Bringaud F, Burton P, Cadag E, Campbell DA, Carrington M, Crabtree J, Darban H, da Silveira JF, de Jong P, Edwards K, Englund PT, Fazelina G, Feldblyum T, Ferella M, Frasch AC, Gull K, Horn D, Hou L, Huang Y, Kindlund E, Klingbeil M, Kluge S, Koo H, Lacerda D, Levin MJ, Lorenzi H, Louie T, Machado CR, McCulloch R, McKenna A, Mizuno Y, Mottram JC, Nelson S, Ochaya S, Osoegawa K, Pai G, Parsons M, Pentony M, Pettersson U, Pop M, Ramirez JL, Rinta J, Robertson L, Salzberg SL, Sanchez DO, Seyler A, Sharma R, Shetty J, Simpson AJ, Sisk E, Tammi MT, Tarleton R, Teixeira S, Van Aken S, Vogt C, Ward PN, Wickstead B, Wortman J, White O, Fraser CM, Stuart KD, Andersson B.
Science. 2005 Jul 15;309(5733):409-15.
PMID: 16020725
29: Comparative genomics of trypanosomatid parasitic protozoa.
El-Sayed NM, Myler PJ, Blandin G, Berriman M, Crabtree J, Aggarwal G, Caler E, Renauld H, Worthey EA, Hertz-Fowler C, Ghedin E, Peacock C, Bartholomeu DC, Haas BJ, Tran AN, Wortman JR, Alsmark UC, Angiuoli S, Anupama A, Badger J, Bringaud F, Cadag E, Carlton JM, Cerqueira GC, Creasy T, Delcher AL, Djikeng A, Embley TM, Hauser C, Ivens AC, Kummerfeld SK, Pereira-Leal JB, Nilsson D, Peterson J, Salzberg SL, Shallom J, Silva JC, Sundaram J, Westenberger S, White O, Melville SE, Donelson JE, Andersson B, Stuart KD, Hall N.
Science. 2005 Jul 15;309(5733):404-9.
PMID: 16020724
30: Genomic and proteomic approaches for Chagas' disease: critical analysis of diagnostic methods.
Huete-Pérez JA, Flores-Obando RE, Ghedin E, Caffrey CR.
Expert Rev Mol Diagn. 2005 Jul;5(4):521-30. Review.
PMID: 16013970
31: The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode.
Foster J, Ganatra M, Kamal I, Ware J, Makarova K, Ivanova N, Bhattacharyya A, Kapatral V, Kumar S, Posfai J, Vincze T, Ingram J, Moran L, Lapidus A, Omelchenko M, Kyrpides N, Ghedin E, Wang S, Goltsman E, Joukov V, Ostrovskaya O, Tsukerman K, Mazur M, Comb D, Koonin E, Slatko B.
PLoS Biol. 2005 Apr;3(4):e121. Epub 2005 Mar 29.
PMID: 15780005
32: A virus with big ambitions.
Ghedin E, Fraser CM.
Trends Microbiol. 2005 Feb;13(2):56-7. No abstract available.
PMID: 15680763
Porter-Kelley JM, Gerald NJ, Engel JC, Ghedin E, Dwyer DM.
Traffic. 2004 Nov;5(11):868-83.
PMID: 15479452
34: Role of viral regulatory and accessory proteins in HIV-1 replication.
Seelamgari A, Maddukuri A, Berro R, de la Fuente C, Kehn K, Deng L, Dadgar S, Bottazzi ME, Ghedin E, Pumfery A, Kashanchi F.
Front Biosci. 2004 Sep 1;9:2388-413. Review.
PMID: 15353294
35: Mechanisms of HTLV-1 transformation.
Kehn K, Berro R, de la Fuente C, Strouss K, Ghedin E, Dadgar S, Bottazzi ME, Pumfery A, Kashanchi F.
Front Biosci. 2004 Sep 1;9:2347-72. Review.
PMID: 15353292
Guiliano DB, Hong X, McKerrow JH, Blaxter ML, Oksov Y, Liu J, Ghedin E, Lustigman S.
Mol Biochem Parasitol. 2004 Aug;136(2):227-42.
PMID: 15478801
Ghedin E, Pumfery A, de la Fuente C, Yao K, Miller N, Lacoste V, Quackenbush J, Jacobson S, Kashanchi F.
Retrovirology. 2004 May 25;1:10.
PMID: 15169557
38: Gene synteny and evolution of genome architecture in trypanosomatids.
Ghedin E, Bringaud F, Peterson J, Myler P, Berriman M, Ivens A, Andersson B, Bontempi E, Eisen J, Angiuoli S, Wanless D, Von Arx A, Murphy L, Lennard N, Salzberg S, Adams MD, White O, Hall N, Stuart K, Fraser CM, El-Sayed NM.
Mol Biochem Parasitol. 2004 Apr;134(2):183-91.
PMID: 15003838
39: First sequenced genome of a parasitic nematode.
Ghedin E, Wang S, Foster JM, Slatko BE.
Trends Parasitol. 2004 Apr;20(4):151-3. Review. No abstract available.
PMID: 15099548
Bringaud F, Biteau N, Zuiderwijk E, Berriman M, El-Sayed NM, Ghedin E, Melville SE, Hall N, Baltz T.
Mol Biol Evol. 2004 Mar;21(3):520-8. Epub 2003 Dec 23.
PMID: 14694076
41: The sequence and analysis of Trypanosoma brucei chromosome II.
El-Sayed NM, Ghedin E, Song J, MacLeod A, Bringaud F, Larkin C, Wanless D, Peterson J, Hou L, Taylor S, Tweedie A, Biteau N, Khalak HG, Lin X, Mason T, Hannick L, Caler E, Blandin G, Bartholomeu D, Simpson AJ, Kaul S, Zhao H, Pai G, Van Aken S, Utterback T, Haas B, Koo HL, Umayam L, Suh B, Gerrard C, Leech V, Qi R, Zhou S, Schwartz D, Feldblyum T, Salzberg S, Tait A, Turner CM, Ullu E, White O, Melville S, Adams MD, Fraser CM, Donelson JE.
Nucleic Acids Res. 2003 Aug 15;31(16):4856-63.
PMID: 12907728
42: Identification of non-autonomous non-LTR retrotransposons in the genome of Trypanosoma cruzi.
Bringaud F, García-Pérez JL, Heras SR, Ghedin E, El-Sayed NM, Andersson B, Baltz T, Lopez MC.
Mol Biochem Parasitol. 2002 Sep-Oct;124(1-2):73-8.
PMID: 12387852
Shakarian AM, Joshi MB, Ghedin E, Dwyer DM.
J Biol Chem. 2002 May 17;277(20):17994-8001. Epub 2002 Mar 6.
PMID: 11882658